Viral pneumonia case study 9% Objectives: To analyse the clinical features, inflammatory markers and radiographs of community-acquired pneumonia (CAP) cases with lobe or multi foci infiltration; with a special focus on factors which allow the differential diagnosis of viral and mycoplasma pneumonia. However, the viral etiology and clinical features of patients with viral pneumonia in China remain unclear. 31·7% of cases in the PERCH study had wheeze on auscultation, 52·5% had no consolidation or opacification on chest x-ray, and 31·1% had RSV, suggesting that many The HMPV seasonal outbreak in China, caused by respiratory syndrome human metapneumovirus (HMPV), began with an increase in cases in Beijing, China in December 2024. ARDS is one of the most frequently observed complications of COVID-19 . The characteristics of the included studies are summarised below in Table 2. pyogenes pneumonia, reflecting virus-induced epithelial damage in the Rammelkamp CH. Respiratory viruses substantially contribute to pneumonia in both adults and children, and when systematically tested for, Epidemiology of viral pneumonia. 7% for these three groups. Case patients had diagnoses of lower respiratory tract infection (LRTI; including pneumonia or nonpneumonia LRTI diagnoses), with viral infections detected by multiplex polymerase chain reaction testing. 9% of Delta and 19. Three studies examined the direct effects of PCV13 against viral LRTI in Most clinicians treated patients with SARS-CoV-2 infections with prophylactic antibiotics (63. 15 In a different study conducted in Mozambique, viruses were detected in 49% of children with severe pneumonia, and in this case, HRV (41 Although not all cases manifest with typical patterns, most typical imaging patterns of viral pneumonia can be classified according to viral families. Bangladesh Introduction. NICE Guidance. 0% of Omicron cases had COVID-19 pneumonia. 18 among booster recipients among these Delta infections. Objectives To compare the pulmonary chest CT findings of patients with COVID-19 pneumonia with those with other types of viral pneumonia. Hemolytic Streptococcal Pneumonia and Empyema: A Study of 55 Cases with Special Reference to Treatment. Methods We retrospectively recruited patients hospitalised with viral Backgrounds Early and accurate diagnosis of pediatric pneumonia in primary health care can reduce the chance of long-term respiratory diseases, related hospitalizations and mortality while lowering medical costs. Oncol. 1-4 In the past there were relatively limited ranges of diagnostic tools for viral pneumonia such as antibody detection only, thereby compromising the ability to identify the causative virus in the CAP cases. 5% (n = 3,072) in all clinical reports of viral pneumonia included in this review. Many studies have reported associations between corticosteroid therapy and mortality, nosocomial infection, Although corticosteroid therapy was reported to improve the clinical features of viral pneumonia in some cases, there is no confirmed evidence of corticosteroid therapy reducing RESULTS: In viral pneumonia, steroid decreases the cytokines, but prolongs vthe viral replication period. Viral pneumonia case study one in the news Background: Pediatric pneumonia remains a significant health challenge, while the viral risk factors for adverse outcomes in pediatric pneumonia are not yet fully clear. 1186 those with MP infection and documented viral infection, treated with only macrolides; Group IV included those with viral pneumonia without documented MP A viral CAP was defined as a pneumonia case in which at least one virus was microbiologically detected in a respiratory sample. In cases of bacterial pneumonia, initial antibiotic treatment is important for infection resolution [], and a shorter time between In this prospective, open-label, multicenter study, subjects aged 18–80, diagnosed with viral pneumonia received either standard supportive treatment alone (Control-Group) or combined with iNO The identification of etiology is very important when managing patients with community-acquired pneumonia (CAP). Relationship between vitamin D status and viral pneumonia in children. Organizing pneumonia (OP), formerly named bronchiolitis obliterans, is a clinical, radiological, and histological entity that is classified as an interstitial lung disease. During the last two decades, three outbreaks of coronavirus-associated pneumonia, namely Severe Acute Respiratory Syndrome, Middle-East Respiratory Syndrome, and the ongoing Coronavirus Background Pneumonia is one of the principal reasons for incidence and death in the world. However, reports on patients co-infected with avian influenza virus and SARS-CoV-2 are scarce. 2 However, according to a 10-year study on respiratory tract surveillance in China, Mycoplasma pneumoniae is the atypical pathogen with the highest detection rate in 5 Harm of corticosteroid therapy in influenza pneumonia. (SARS) is a new emerging disease that has affected many countries, with more than 3500 cases reported. Ann. A case was reported with a literature review, and a comprehensive literature search was performed using the PubMed/MEDLINE and Scopus databases. Student Guide . Case Most have a viral etiology and do not but it may also result from clinical practices associated with overtesting and overtreatment. Recent findings: Emphasis is given to the pathogenesis of bacterial and viral co-infection including specific highlighting on influenza, rhinovirus, respiratory syncytial Definitions are sometimes incorrectly used in daily routine practice and under study conditions. CDC on Viral pneumonia case study one. Methods This retrospective study analyzed two publicly available dataset that contain X-ray images of pneumonia cases and normal cases. In this study, we investigated whether several viral agents are associated with life‐threatening events in hospitalized patients with pneumonia using a case‐control study. studies regarding the viral etiology in CAP are scarce. Serum endocan levels, WBC and neutrophil counts, and PCT and CRP levels were significantly higher in children with bacterial pneumonia than in children with viral The diseases encompassed within WHO's clinical definition of pneumonia include bacterial and viral pneumonia, acute viral bronchiolitis, and bacterial and viral bronchitis. Symptoms of viral pneumonia are similar to that of bacterial pneumonia, although studies Cite this: Three Cases of Community-Acquired Pneumonia: Is It Bacterial, Viral, or Fungal? - Medscape - Sep 18, 2023. Grossly, lung lobes were mottled red and pink and were heavy, wet and congested – lesions consistent with pneumonia. The utility of clinical, microbiological and In this nationally-representative case-crossover study of 236,987 pneumonia deaths of specific infectious causes from all 31 province-level and 2844 county-level administrative units across the Chinese mainland, we provided the evidence that non-optimum ambient temperature could increase the risk of pneumonia mortality of various infectious Rationale: World healthcare frequently faced severe viral pneumonia cases in the last decades, due to pandemic situations such as H1N1, MERS-CoV, and SARS-COVID-19. We undertook a case-control study among adults at Kaiser Permanente Southern California between 2015 and 2019. Skip to main content. 66% of patients had totally normal chest X-ray at admission. Introduction Chronic lung disease is a major cause of morbidity in African children with HIV infection; however, the microbial determinants of HIV-associated chronic lung disease (HCLD) remain poorly understood. One month earlier, he had returned from a trip to Southe Purpose of review: We aim to review the epidemiology of pneumonia with bacterial and viral coinfection, the pathogenesis and clinical impact of coinfection along with the current state of treatment and outcomes. E-paper Today's News বাংলা. 2%, after cases of dual bacterial or viral infections were eliminated. 7, 8, 9 Although no studies have reported the incidence of ARDS specifically caused by viral pneumonia, epidemiologic surveys of adults admitted However, after the outbreak of COVID-19, few studies were conducted on non-COVID-19 viral pneumonia. The use of chest radiographs (CXRs) to identify pneumonia cases is also imperfect but understood to Unfortunately, this study did not correlate the IHC positivity with specific histological features such as areas of acute versus organising DAD or bronchopneumonia. Objectives : This study aim to compare nursing process in 2 cases of VAP patient. Clinical assessments for diagnosing pneumonia are sensitive but nonspecific, resulting in the inclusion of many nonpneumonia cases []. Taking advantage of the largest death registry in the world, this nationwide, individual-level, case-crossover study established strong and immediate connections between short-term exposures to PM 2. 1016/S0140-6736(19)30721-4. To explore the relationship between atmospheric pollution and hospital visits for pneumonia Pulmonary consolidation is a non-specific term for pulmonary opacities seen on radiography that are the result from a process that fills the alveolar spaces (further discussion here). Distinguishing bacterial pneumonia from viral pneumonia is critical to providing effective treatment but remains a significant challenge. In the randomly selected sample (n = 58), the sensitivities of three radiologists from China and four radiologists from the United States were This paper is a case study of a 52 year old female who was in the hospital for a scheduled gastric bypass surgery. Methods This retrospective, observational study included all adult patients with confirmed influenza From the June 2020 Newsletter: The first case is a 2-week-old female Ringtail lemur (Lemur catta) that was found dead after three other neonatal lemurs from the same cohort died the previous week. 1 The COVID-19 Coronavirus. For all chest CT scans (n = 424), the accuracy of the three radiologists from China in differentiating COVID-19 from non-COVID-19 viral pneumonia was 83% (350 of 424), 80% (338 of 424), and 60% (255 of 424). As we performed a case‐control study, this may lead to our samples less representative of the general population. 1 27 patients were initially reported, which was subsequently revised to 41 on Jan 11, 2020, with seven severe cases and one death. Covid-19 is a viral disease caused by SARS-CoV-2 1. 0000000000000698. Methods This retrospective review includes 154 patients with RT-PCR-confirmed COVID-19 pneumonia diagnosed between February 11 and 20, 2020, and 100 patients with other types of viral pneumonia diagnosed between Background The World Health Organization's (WHO) case definition for childhood pneumonia, composed of simple clinical signs of cough, difficult breathing and fast breathing, is widely used in resource poor settings to guide management of acute respiratory infections. CT findings are non-specific and diverse and have been described without distinction between AIDS and non-AIDS patients. In This case-control study was conducted at Xiengkhuang Provincial Hospital (19° 26′ 47″ N, 103° 12′ 11″ E), Laos, from 24th June 2019 to 24th June 2020 with case to control ratio of 1:1. Given that the treatment protocols of specific virus still lag behind for viral pneumonia, and short of A study of 211 French children with rhinovirus infection revealed bronchiolitis or bronchitis in 25. This case study exemplifies the potentially serious consequences of treatment failure following prescription of a macrolide for community-acquired bacterial pneumonia. a case-control study in China Transl Pediatr. Methods: During April 2015-December 2017, we conducted a case-control study among severe acute malnourished (SAM) children Of 826 eligible cases, 405 were Delta and 421 were Omicron cases; 48. 1% of cases of pneumonia. 6% and pneumonia in 6. T. The most common CT findings are pure ground-glass opacity (GGO), GGO with reticular and interlobular septal Background Influenza viruses cause pneumonia in approximately one-third of cases, and pneumonia is an important cause of death. doi: 10. In this nationally-representative case-crossover study of 236,987 pneumonia deaths of specific infectious causes from all 31 province-level and 2844 county-level administrative units across the Chinese mainland, we provided the evidence that non-optimum ambient temperature could increase the risk of pneumonia mortality of various infectious causes and contribute a On examination in the NICU, the patient's temperature was 37. We found that Jul 10, 2024 · American Roentgen Ray Society Images of Viral pneumonia case study one All Images X-rays Echo & Ultrasound CT Images MRI; Ongoing Trials at Clinical Trials. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. According to the World Health Organization, lower respiratory tract infections account for approximately 7% of deaths per year worldwide. Here we aimed to identify genetic risk loci for CAP The aim of this study was to describe the clinical outcomes and virological monitoring of the first five COVID-19 patients admitted to the intensive care unit of Bichat-Claude Bernard University Hospital, Paris, France, for severe pneumonia related Objectives To analyse the clinical features, inflammatory markers and radiographs of community-acquired pneumonia (CAP) cases with lobe or multi foci infiltration; with a special focus on factors which allow the differential diagnosis of viral and mycoplasma pneumonia. FDA on Viral pneumonia case study one. Beneficial effect is shown in varicella pneumonia with decreased hospital stay,but in H1N1infected patients, a trend of increasing hospital-acquired pneumonia!, duration of mechanical ventilation, and hospital mortality,especially in patients receiving early steroid therapy. Staphylococcus aureus accounted for the majority (n=18; 56. Setting: Retrospective chart review of CAP cases in a large university teaching hospital. Because the number of children with influenza A virus (n = 42, 5%) was low in our study, the sample size may be underpowered to conclude the effect of vaccination on influenza virus‐associated pneumonia. Setting Retrospective chart review of CAP cases in a large university teaching hospital. 296. A single-center study of children hospitalized with acute respiratory infections found that children in certain racial and ethnic groups were more likely to receive broad-spectrum antibiotics than Pneumococcal pneumonia is a possibility, despite the patient's immunization; one study showed the incidence of uncomplicated infection to be essentially unaffected by vaccination in the group 5 to In a study of severe and very severe pneumonia conducted in Kenya and using multiplex PCR, a virus was detected in 56% of children less than 12 years old; RSV was most common and detected in 34% of children. A study involving the use of chest CT for differentiating SARS-CoV-2 pneumonia from other types of viral pneumonia found that radiologists who were blinded to RT-PCR results could correctly distinguish cases of SARS For these case studies, we have selected our classes from Normal, Covid-19, Viral Pneumonia, and Bacterial Pneumonia. 1, 2 Those at risk for more severe disease include the very To assess the effect of pneumonia on the risk of mortality and other clinical outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods. Methods: Based on the national death registry covering all counties in Chinese mainland, we conducted an individual-level case-crossover study in China from 2013 to 2019. 69 In one study, viral co-infections were associated with more severe pneumonia than were single infections, when rates of admission were looked at. 48 among those completing primary vaccination <180 days and 0. Assess for comorbidities that increase risk of complicated infection including Community-acquired pneumonia (CAP) is a major cause of morbidity and mortality [], and its incidence is only increasing with an aging global population []. Objectives: 1. Viral-bacterial co-infection Jul 1, 2024 · This nationwide, individual-level, case-crossover study conducted across all counties in mainland China presents the most convincing epidemiological proof thus far, demonstrating for the first time an association between short-term exposure to PM 2. Bacterial Telehealth Management of Urostomy Postoperative Complications: A Case Study J Wound Ostomy Continence Nurs. Empiric antibacterial therapy is recommended for most patients hospitalized for CAP [], as it is difficult to identify the Purpose Development and assessment the deep learning weakly supervised algorithm for the classification and detection pneumonia via X-ray. The former research mainly concentrated on specific sources of patients. Moderate cases had manifestations of pneumonia along with any symptoms of COVID-19 such as fever, cough, or other respiratory symptoms. [PMC free article] [Google Scholar] 11. Exposures were assigned at residential addresses for each decedent. All Aims: The virus is common in patients with viral pneumonia. 1940;56:31–56. Commonly described findings include: A majority of approximately 60% of all study participants with viral pneumonia were exclusively infected with SARS-CoV-2. Pediatr Allerg Immunol Pulmonol 2017;44:86 The common constitutional symptoms of viral pneumonias are fever, chills, nonproductive cough, rhinitis, myalgias, headaches, and fatigue. 2 Some patients were reported to have radiographic ground-glass lung changes; normal or lower than In this study, we aimed to assess the arterial blood gas (ABG) and acid-base patterns in COVID-19 patients admitted to a tertiary care hospital. 43 %, as well as precision and recall values of 98. 5 million adults are The diagnosis of pneumonia in children is challenging due to overlapping clinical features of viral and bacterial etiologies of pneumonia, in addition to other lower respiratory tract pathologies. 1 Viruses are a common cause of community-acquired pneumonia, particularly among children. 12 The incidence and outcome of these viral pneumonias can vary significantly based on the intensity and duration of T-cell–mediated pneumonia while compared between 178 cases and 174 controls. Our study findings may help in planning further studies targeting vaccines or drugs against common respiratory viruses responsible for pneumonia among SAM children Acute viral tract infections can be associated with the occurrence of S. Trans Am Clin Climatol Assoc. 7 million globally. This issue provides guidance for the management of pediatric community-acquired pneumonia as well as associated complications including pleural effusion/empyema (Case-control study; 121 cases, 240 Even a short course of oral corticosteroids in the preceding month for an asthma exacerbation, such as in this case study, is a risk factor for ARDS and mechanical ventilation. Evaluating pneumonia etiology among malnourished children may help improve empiric treatment guidelines. 8, 9, This case–control study was approved by the Institutional Review Board of Taipei Veterans General Hospital. 1 The most severe common LRTI in the UK is community-acquired pneumonia (CAP), which for hospitalised patients has a mortality of 8%2 and the incidence of which is increasing as the Pneumonia Cases in Bangladesh 2024: Three-year-old Anisha Anju was struggling to breathe in the pneumonia ward of Dhaka Shishu Hospital and Institute. Participants 126 paediatric Update 2022: A meta-analysis of six randomized controlled trials involving 834 patients comparing doxycycline to macrolides and fluoroquinolones for the treatment of non-severe community acquired pneumonia in adults found similar efficacy and adverse event rates, with lower length of hospitalization and lower cost of antimicrobial agent in the doxycycline PeopleImages / iStock. The study enrolled 334 intensive care unit patients who developed life This case report highlights a case of rapidly progressive severe ARDS secondary to COVID-19 viral pneumonia, and serves as warning to clinicians about the speed at which respiratory failure with associated multiorgan dysfunction can occur. Strikingly, nearly half the patients had shifting radiographic shadows. Background: In Bangladesh, pneumonia has a higher mortality among malnourished children aged <5 years. The study aims to establish an early Influenza-A viral pneumonia and healthy cases (618 transverse-section CT samples before data augmentation). [1] Viruses are the most common cause of pneumonia in children, while in adults bacteria are a more common Viral pneumonia is one the most frequent respiratory diseases among very young people and the elderly, Chen Y. 9 million deaths each year. Mild cases had one or more subjectively mild symptoms of infection, but did not have any signs of pneumonia on imaging. 2. [PMC free article] The proposed study is the first case–control study of pneumonia aetiology in Australia in post PCV vaccination era, where 250 radiologically confirmed hospitalised pneumonia cases (n=250) will be compared with 250 age group frequency-matched healthy controls for both the presence of respiratory pathogens and quantitative load of pathogens. We herein report two cases of HRV pneumonia diagnosed by multiplex polymerase chain reaction (PCR) from bronchoalveolar lavage (BAL) fluid. 4%, respectively, compared with the rates before the COVID-19 Mixed viral-bacterial infections in adults with community-acquired pneumonia seem to be reported less frequently than those in children. If viral-induced damage was the primary While the typical imaging features of viral pneumonias include hyperinflation, increased interstitial markings, and subsegmental atelectasis, lobar consolidation is a chest imaging feature in viral pneumonia including those caused by adenovirus. Results: The study sample consisted of 41 children, of whom 21 had bacterial pneumonia and 20 had viral pneumonia, whereas the control group consisted of 47 healthy children. . Data were collected form medical records form, relative interview, and Characteristics of studies. The etiology of CAP is complex, with bacteria and viruses playing major roles []. 28 Our findings in COVID‐19 pneumonia are similar to those observed by Shieh et al. Among Influenza virus, rhinovirus, and adenovirus frequently cause viral pneumonia, an important cause of morbidity and mortality especially in the extreme ages of life. 1097/WON. 2020;31:894–901. [1] Pneumonia can be caused by bacteria, viruses, fungi or parasites. Methods: We applied time-stratified case–crossover analyses with distributed lag Pneumonia Etiology Research for Child Health (PERCH) Study Group Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study. 2020. Molecular diagnostic tests have greatly increased our understanding of the role of viruses in pneumonia, and findings indicate that the incidence of viral pneumonia has been underestimated. Viral pneumonia may clear up on its own; however, when severe, it can be life-threatening. Methods: A matched case-control study of pediatric patients with pneumonia was carried out in Beijing, China, between 2007 and 2015. In 26 of these 46 patients (60. 7 cases per 10,000 children and higher among children In order to distinguish pneumonia from CXRs [1], Hashmi presented a weighted classifier made up of the DL models Xception, InceptionV3, ResNet18, MobileNetV3 and DenseNet121. 700 test images were used where 400 for pneumonia cases and 300 for normal cases [66]. The aim was to identify risk factors associated with severity and those that could predict the development of pneumonia. Pneumonia is a common illness with estimates of approximately 450 million cases per year. Although a definite diagnosis cannot be achieved on the basis of imaging features alone, recognition of viral pneumonia patterns may aid in differentiating viral pathogens, thus reducing the use In a study of viral infections in patient who had undergone HSCT, the incidence of influenza ranged from 14% to 52%, RSV from 14% to 48%, adenovirus from 2% to 21%, and PIV from 11% to 49% of all viral isolates. 6°C, the blood pressure 60/30 mm Hg, the pulse 174 beats per minute (normal, 80 to 180), and the respiratory rate 56 breaths per Despite the importance of paediatric pneumonia as a cause of short and long-term morbidity and mortality worldwide, a reliable gold standard for its diagnosis remains elusive. In infectious diseases, host genetics plays a critical role in susceptibility and immune response, and the immune pathways involved are highly dependent on the microorganism and its route of infection. Although a definite diagnosis cannot be achieved on the basis of imaging features alone, recognition of viral pneumonia patterns may aid in differentiating viral pathogens, thus reducing the use Background: It remains unknown how ambient temperature impact pneumonia of various infectious causes. A mixed infection was defined as a CAP in which a virus was detected together with either bacteria or fungi. This was a retrospective case–control study. The definition is also commonly used as an entry criteria or endpoint in different intervention and The diagnosis of pneumonia in children is challenging because there is no single method with high sensitivity and high specificity [1, 2]. annonc. 9% due to secondary infections was observed (53 of 482). 2. The overall accuracy of the deep learning models were 86. A recent study involving blood microarray data from 107 children diagnosed with pneumonia has identified eight unique transcriptomic signatures. Due to reasons including methodological variance, not all studies reported the average age of their Viral pneumonia has been a serious threat to global health, especially now we have dramatic challenges such as the COVID-19 pandemic. PubMed, EMBASE and Scopus were screened for observational cohort and case-control studies that reported outcomes in AECOPD patients with and without pneumonia. 7%, n = 1,901), compared to 73. Despite advances and new interventions in supportive care, the mortality rate among CAP patients has not decreased in the past decades (Restrepo et al. in H1N1 influenza viral pneumonia, where influenza A viral RNA by RT–PCR and antigen by IHC . 15 In a study in which community-acquired pneumonia was grouped as pneumococcal, atypical, and viral Community-acquired pneumonia remains a major public health issue. 5-10 and increased mortality risks associated with viral pneumonia and bacterial pneumonia. The aim of this study was to assess the value of blood biomarkers, clinical symptoms and their combination in assisting discrimination of pneumonia The chest radiograph shows patchy peribronchial opacities bilaterally suggestive of atypical pneumonia. Under the microscope, large airways were Background Community-acquired pneumonia (CAP) is associated with high morbidity and hospitalization rate. Identify characteristics and relevant review of systems that may indicate pneumonia including whether cough is productive and presence of constitutional symptoms. Methods: We did a multi-site, international case-control study in nine study sites in seven countries: Bangladesh, The Gambia, Kenya, Mali, South Africa, Thailand, and Zambia. Introduction. 2023 Jun 30;12(6):1192-1203. According to the findings of a previous study, among patients with systemic symptoms, A viral pneumonia. 26 % and The majority of patients infected with respiratory pathogens such as influenza viruses and Mycoplasma pneumoniae (M. 2020 Sep/Oct;47(5):456-457. Co-infection of influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to poor prognosis of patients during the COVID-19 epidemic. US National Guidelines Clearinghouse. Guo LY, Li W, Cheng XF, et al. Community-acquired pneumonia (CAP) is one of the most common reasons for hospitalization and mortality among adults (Mandell, 2004; Zar et al. We conducted a case–control study to investigate the prevalence and densities of respiratory microbes among pneumococcal conjugate vaccine Study protocol and selection of patients. 1 day ago · Cytomegalovirus (CMV) pneumonia is an uncommon presentation of CMV among patients with HIV/AIDS, particularly in co-infection with Pneumocystis jirovecii pneumonia (PCP). Viral pneumonia has historically been a significant cause of morbidity and mortality for humankind. 2019;394:757–79. 19,20,77–85 In one study, both viral and bacterial pathogens were noted in 35 (14%) of 242 cases. The differential for the radiologic finding of pulmonary consolidation includes blood (pulmonary hemorrhage), pus (infection, i. Considering that circumstances, International Centre for Diarrheal Disease Research, Bangladesh (icddr,b) developed an innovative day care management approach as safe, effective and less expensive alternative to hospital Viral pneumonia is a pneumonia caused by a virus. Pneumonia, Viral / epidemiology* Pneumonia, Viral / prevention & control Pneumonia, Viral / transmission A 57-year-old man was admitted to the intensive care unit in the winter because of severe pneumonia and acute hypoxemic respiratory failure. Indeed, the 1918 influenza pandemic caused over 50 million deaths worldwide and its pathobiology is still incompletely understood []. While numerous reports have focused on novel influenza viruses, there is a paucity of case reports detailing seasonal influenza viral infections in this patient population. The quality of life and assumed life expectancy was decreased with Cytomegalovirus pneumonia is a type of viral pneumonitis and occurs due to infection with cytomegalovirus (CMV), which is a member of the Herpetoviridae family. Pneumonia is an infection that causes inflammation in one or both lungs. The viral cohort consisted of 22 cases of SARS-CoV-2 and 18 cases of The study by Bhuiyan et al. This paper explores Pneumonia and the respiratory disease process associated with bacterial and viral pathogens most commonly located in the lung. . 3 The aim of our study was to measure the frequency of antibiotic prescribing in children 12. Diagnosis of pneumonia was based on clinical symptoms and CT imaging. 0% and 99. , 2013). Across all 14 studies, a total of 611 cases of MD (x ¯ = 44) were matched to 373 controls (x ¯ = 27), corresponding to an average of eight cases of MD for every five controls. Dec 11, 2024 · Seasonal influenza is prevalent globally, particularly during winter months. A study from the Netherlands demonstrated that This section provides a brief review of literature tied to this work. About 200 million cases of viral community-acquired pneumonia occur every year—100 million in children and 100 million in adults. 2022 Mar 9 Viruses and bacteria from the nasopharynx are capable of causing community-acquired pneumonia (CAP), which can be difficult to diagnose. symptoms and treatments most commonly viewed in patient cases of Pneumonia Lower respiratory tract infections (LRTIs) remain a common cause of respiratory mortality, responsible annually for approximately 40 000 deaths in the UK and 2. In this regard, several studies showed that prevalence of viral CAP varies from 15% to 35% [2,7,9,10,, In this study, we estimated causes of pneumonia in young African and Asian children, using novel analytical methods applied to clinical and microbiological findings. In Pakistan, studies regarding the viral etiology in CAP are scarce. Worldwide, 489 million lower respiratory infections occurred in 2019. 8% of cases of unspecified LRTI and 48. It was brought to public attention when the Chinese Center for Disease Control and Prevention published data showing that respiratory infections of human metapneumovirus had risen Community-acquired pneumonia (CAP) may result from infection by recognized bacterial pathogens, respiratory viruses, bacteria traditionally regarded as commensal bacteria but recently shown to cause pneumonia, or bacterial/viral coinfection [1,2,3,4,5]. A stepwise logistic regression analysis of 88 cases was performed to assess independent predictors which allowed the differential diagnosis of viral and mycoplasma community-acquired pneumonia (CAP). It is well documented that this disease causes severe, often fatal complications in hemodialysis patients. All patients with COVID-19 pneumonia were hospitalized at the West Court of Union Hospital of Huazhong Case Discussions _____ Pneumonia . Furthermore, the consequential treatment dilemmas currently faced by physicians are briefly discussed. 34 We therefore reviewed all cases and used the terms pneumonia and LRI as standardized and defined in international guidelines. Over a period of 1 year, a retrospective study was carried out in our hospital. Viral pneumonia is increasingly recognized as a cause of hospital-acquired pneumonia, with comparable mortality to bacterial pneumonia []. pneumoniae) are asymptomatic or have mild symptoms, and only a proportion of patients manifest symptoms of systemic illness such as fever, fatigue, myalgia, and cough. 5 and PM 2. In a 2010 case-control study conducted in Israel (n=183 adults with CAP, 450 controls), coronaviruses were identified in 24 (13%) patients with Background The H5N1 influenza virus is a cause of severe pneumonia. Viral pneumonia has become a serious threat to public health due to its rapid transmission speed and high mortality rate. 34% of the overall study cases, while the remaining 27. 2 Some patients were reported to have radiographic ground-glass lung changes; normal or lower than Viral pneumonia is a common complication of influenza-like illnesses and is a complication of SARS-COV-2. Viral pneumonia is defined as a disease entity wherein there is the viral causation of oxygen and carbon dioxide gas exchange abnormalities at the level of the alveoli, secondary to viral-mediated and/or immune response-mediated inflammation. We aimed to investigate whether This case study aimed to represent the actual scenario of severe childhood pneumonia case management at community clinic. pneumonia), fluid (heart failure), and cells (cancer). Besides, due to the heterogeneity among regions, there are inconsistencies in the outcome of these surveys. The study enrolled 334 intensive care unit patients who developed life-threatening diseases and 522 controls matched to the sex, age, ethnicity, admission dates, and residing district of the cases suffered from pneumonia. The first dataset from Guangzhou Women and Children’s Medical Center. Methods : Comparative 2 cases VAP patient who were treated at medicine intensive care unit (MICU) of Mahasarakham Hospital. Conclusion Viral etiology of pneumonia in SAM children were mainly attributable to RSV, influenza, HPIV and HMPV. The risks observed were notably highest on Some studies of community-acquired pneumonia have reported that HRV is the most common virus in viral pneumonia (2,3). The pulmonary alveoli fill with fluid or pus making it difficult to breathe. 1 This disease may be idiopathic and of an unknown etiology and may also have many etiologies, such as inflammatory infections, drug responses, pulmonary infarction, pleural lesions, tumor In rare cases, walking pneumonia can prompt brain swelling, kidney issues, and difficulty breathing, and people with lung issues, and weakened immune systems may be especially at risk of The Health Commission of Hubei province, China, first announced a cluster of unexplained cases of pneumonia on Dec 31, 2019. 1 In particular, viruses cause up to 50% of community-acquired pneumonia (CAP) in children and adults, and predispose patients to secondary bacterial pneumonia. 41. 03. Home; News. Objectives: To examine relationships between short-term air pollution exposure and number and severity of pneumonia cases along the Wasatch Front in Utah, a region with periodic high levels of outdoor air pollution. "bilateral-pneumonia-in-transplant-lungs","caption":"Case 3: RSV pneumonia in lung transplant Lastly the study was conducted in a tertiary care hospital with a non-homogeneous sample of patients in which two thirds of the participants had at least one known risk factor for viral pneumonia, such as chronic lung disease (67%), congenital heart disease (29%), and neoplasia (27%), so the results obtained should be taken into account in this Bacterial and Viral Respiratory Tract Microbiota and Host Characteristics in Adults With Lower Respiratory Tract Infections: A Case-Control Study Clin Infect Dis. Only one study, [5] from Australia, reported that by the winter of 2020, the detection rates of respiratory syncytial virus and influenza in Western Australian children decreased by 98. Given the patient's age and radiographic manifestation, chlamydia and mycoplasma are the likely causative organisms. In children, respiratory syncytial virus, rhinovirus, human In this study, there were no differences in outcomes between viral or bacterial causes of pneumonia. Children with pneumonia caused by co-infection with human bocavirus and other viruses have more wheezing than with viral pneumonia associated with a sole pathogen. Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan, China. e. Lancet. 9 million cumulative deaths. with current knowledge coming mainly from case studies and surveillance data from clinical treatment. The COVID-19 coronavirus was initially observed in the Wuhan province of China and is fast spreading to all parts of the world []. All critically ill patients admitted to the intensive care unit (ICU) from January 2018 to December 2020 with a diagnosis of This study specific metabolites and altered pathways in children with viral pneumonia and propose that these findings could contribute to the discovery of new treatments and the development of antiviral drugs. Diseases & Conditions Viral Pneumonia; 2002234753-overview. First CT images were preprocessed for extracting effective pul- Rationale: The relationship between air pollution and pneumonia is poorly understood. For Delta variant infections, compared with full primary vaccination at least six months before Critical combination of initial markers for predicting refractory Mycoplasma pneumoniae pneumonia in children: a case control study Respir Res. The main purpose of this study was to analyze the viral causes and epidemiology of patients with viral pneumonia in Beijing, which can significantly improve the pertinence and accuracy of clinical Although not all cases manifest with typical patterns, most typical imaging patterns of viral pneumonia can be classified according to viral families. 21037/tp-23-199. CAP is treated empirically with antibiotics because the 13 - 50% of single pathogen diagnosed community-acquired pneumonia cases and 8 -27% of mixed bacterial-viral pneumonia. showed that CRP concentration was more than 6 times higher in definite bacterial cases than in viral cases. The attention of the WHO was drawn to a collection of cases of the novel pneumonia discovered in the City of Wuhan, Hubei Province, China. 1016/j. 27–29 Each of the patients in the GIES group was compared with a precisely age-, gender- and length of hospital stay The Health Commission of Hubei province, China, first announced a cluster of unexplained cases of pneumonia on Dec 31, 2019. The traditional role of viral pneumonia was as a disease found predominantly in the very young, the elderly, and those exposed to influenza. This study also showed that elevation of CRP with the presence or absence of clinical symptoms, such as fever (≥38 °C) or the absence of rhinorrhea differentiates bacterial pneumonia from viral pneumonia The classic example of this secondary bacterial infection was the association between influenza and secondary pneumonia cases caused by bacterial pathogens, including pneumococci, during the 1918–1919 influenza pandemic PCV Effect Against Viral LRTI in Adults. Lower respiratory viral infections are a significant source of morbidity and mortality worldwide, causing an estimated 3. For all cases of viral pneumonia, a mortality rate of 10. Patient concerns: The impact of viral infection on lung structure, lung function, and overall mortality was significant. Chest CT is an essential tool of the diagnostic work-up of this respiratory infection 1-5. , et al. Another random control-case study showed when 1- to 36-month-old pneumonia infants orally took a single high-dose of vitamin D3 (100,000 IU), recurrence was basically not found within 3 months. In this study, we conspired a spatiotemporal Strengths and limitations of this study. These signatures can effectively differentiate Mycoplasma pneumoniae infections from other viral and bacterial pneumonias with impressive accuracy, boasting area under the receiver operating Pneumonia is the world’s leading cause of death in children under 5 years old. This case The aim of this case report is to increase the level of suspicion among clinicians regarding the possibility of an association between Miller Fischer syndrome and Mycoplasma pneumoniae infection, which should be considered in any cases of pneumonia that develop neurological manifestations such as ophthalmoplegia and ataxia. Signs of pneumonia and other abnormalities, such as consolidation, hydrothorax, and pneumothorax, were observed on chest radiography in 73. Saturday, January 18, 2025 . For instance, during the COVID-19 pandemic, it is estimated that the cumulative confirmed cases have exceeded 700 million with an approximate of 6. The burden of pneumonia, including that due to respiratory viruses, is markedly higher in the very young (<5 years) and older adults (≥50 years). A matched case-control study of pediatric patients with pneumonia was carried out in Beijing, China, between 2007 and 2015. Conversely, in vitro studies with ciclesonide showed antiviral activity against Covid-19, and there have been reports of clinical effectiveness of inhaled ciclesonide in Case Discussion CT study shows the typical CT findings of COVID-19 pneumonia, which was confirmed by positive laboratory tests. The annual incidence of pneumonia requiring hospitalization was found in one study to be 15. 3%) of cases among bacteria. It Improved diagnostic testing, particularly multiplex reverse transcription polymerase chain reaction (RT-PCR) assays, have increased recognition that respiratory viruses cause critical illness in adults. Imaging findings alone are not specific enough for the definitive diagnosis of viral pneumonia and radiographic patterns can be variable, depending on the specific viral strain, as well as host factors. 3 In a retrospective cohort analysis of adults admitted to an intensive care unit (ICU) with either severe community-acquired or health care–associated pneumonia, 115 of 198 patients had bronchoalveolar lavage and 159 of 198 had nasopharyngeal The host immune response plays a crucial role in viral pneumonia progression and end-organ damage. in some cases, the condition advances to a more severe stage marked by a dysregulated immune response and hyperinflammation, followed by the development of acute respiratory distress syndrome (ARDS Our case-case study showed Omicron variant infection was 66% less likely to result in pneumonia than Delta variant infection. 1 Viruses have historically been the most common cause of community-acquired pneumonia in children, approximately 65%. Epub 2023 Jun 28. Case presentation A 52-year Results. 2019 Aug 23;20(1):193. A high accuracy of 98. 5-10 and increased mortality due to both viral pneumonia and bacterial pneumonia. gov. Viral (including COVID-19) and fungal pathogens may also create the radiological and clinical picture of an atypical pneumonia. Compared with full primary vaccination ≥180 days before infection, the aOR of pneumonia was 0. 1 In the United States, more than 1. We have evaluated our model’s classification performance on various parameters, such as—accuracy, precision, sensitivity, specificity, false-positive rate, and F1-score, as just one parameter is not sufficient enough to Background Concerning viral pneumonia, few large-scale comparative studies have been published describing non-HIV immunocompromised and immunocompetent patients, but the epidemiological characteristics of different viruses or underlying diseases in immunocompromised hosts are lacking. czhea evno ngljfnq mnsf izfg rexmfjf afrvvnta zrtuysc ibr trobe